General Medical Questions and Answers # 3

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1.  Does the presence of HBe antigen indicate that the patient is infectious?
Yes, the presence of the HBe antigen indicates that the patient is infectious

2.  Describe the signs and symptoms of a left sided colorectal cancer?
•    Change in bowel habits
•    Small caliber stools
•    Sgns of obstruction
•    Abdominal mass
•    Heme positive stools with gross blood
•    Constipation  

3.  How common is protein C deficiency in the general population?
Protein C deficiency is seen in 0.2-0.4% of the population

4.  Is there an increased incidence of endometriosis in women with more frequent and prolonged menstrual periods?
There is an increased incidence of endometriosis in women with menstual periods lasting greater than 8 days and cycles that are less than 27 days

5.  What is the mechanism of busulfan?
Busulfan is an oral alkylating agent, not cell cycle specific

6.  Which type of immune reaction is characterized by the antigen reacting with IgE bound to the surface of basophils or mast cells, with secondary degranulation (hay fever)?
Type I (anaphylactic)

7.  What is the most frequent autoimmune complication of chronic lymphocytic lymphoma?
Warm autoimmune hemolytic anemia (15-35%)

8.  What is the most common parasitic worm infection in the U.S.?
Enterobius vermicularis

9.  How does multiple myeloma cause a decreased anion gap?
Multiple myeloma causes increased unmeasured cations

10.  Where are benign colorectal polyps most commonly found?
Rectosigmoid colon

11.  How often does Addison's disease occur secondary to autoimmune destruction of the adrenal glands?
Approximately 80% of patients with Addison's disease have had autoimmune destruction of their adrenal glands

12.  What is the sign that describes the murmur of tricuspid insufficiency increased with inspiration?
Carvello sign

13.  What is the virus which causes smallpox?
The variola virus is known to cause smallpox

14.  What are the most common causes of eosinophilia?
Allergic or atopic diseases.

15.  How often will herpes simplex 1 of the lips or perioral region recur?
Approximately 20-40% of primary herpes simplex 1 infections of the lips or perioral regions will recur.

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